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Chinese traditional patent medicine might change global strategy of treating RA
CopyFrom: PUMCH UpdateTime: 2015-06-15 Hits: 120 Font Size: SmallBig

For rheumatoidarthritis (RA) at active stage, the effect of using tripterygiumglycosides alone is not worse than using methotrexate alone, but the two in combination produces a noticeably better effect than methotrexate alone, according to a research of PUMCH.

In early 2012, the Department of Rheumatology and Clinical Immunology, led by Professor Zhang,Xuan, in cooperation with nine rheumatology research centers in China, carried out a clinical research comparing the effects of tripterygiumglycosides and methotrexate. After 24-week treatment of 207 patients, tripterygiumglycosides alone produced an effective rate of 55.1%, higher than the 46.4% of methotrexate alone, while the two in combination reached an effective rate of 76.8%.


"The findings are definitely of interest, as there was a clear treatment effect. This is a compound of interest for further study and development," said Dr. Eric L. Matteson, chair of the Division of Rheumatology and a professor of medicine at Mayo Clinic.

The findings were recently published in Ann Rheum Dis and BMJ also printed the news.