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临研所概况

疑难重症及罕见病全国重点实验室

生物医学技术中心

转化医学国家重大科技基础设施

国家临床医学研究中心（建设中）

新闻动态

临研新闻

通知公告

科学普及

科研服务

技术服务

仪器平台

共享实验室

开放研究计划与对外合作

研究成果

临床研究成果

国家科技进步奖

研究者介绍

合作与交流

合作与交流

学术活动

人才招聘

协和医学杂志

抗疫专题展

协和医学杂志

协和展览

抗疫专题展

张孝骞展

病历展

院史馆

Synthesis of PEGylated hyaluronic acid for loading dichloro(1,2-diaminocyclohexane) platinum(II) (DACHPt) in nanoparticles for cancer treatment

An effective tumor-targeting strategy utilizing hypoxia-sensitive siRNA delivery system for improved anti-tumor outcome

Nanomedicine–based combinational anticancer therapy between nucleic acids and small-molecular drugs.

A thermoresponsive nanocarrier for mitochondria-targeted drug delivery.

Light-triggered PEGylation/dePEGylation of the nanocarriers for enhanced tumor penetration.

D-arginine-loaded metal-organic frameworks nanoparticles sensitize osteosarcoma to radiotherapy.

Mitochondrial temperature-responsive drug delivery reverses drug resistance in lung cancer.

The nanoformula of zoledronic acid and calcium carbonate targets osteoclasts and reverses osteoporosis.

Liu J, Wang Z, Wu K, Li J, Chen W, Shen Y, Guo S. Biomaterials. 2015;53:592-9.

Wang Z#, Liu J#, Wu K, Shen Y, Mao A, Li J, Chen Z, Guo S.Gastrointest Endosc. 2015 Jul;82(1):153-160.e1.

Liu J#, Ding L#, Zhai X, Wang D, Xiao C, Hui X, Sun T, Yu M, Zhang Q, Li M, Xiao X. Front Microbiol.

Liu J#, Fu J#, Xie Z#, Ding L, Wang D, Yu M, Zhang Q, Xie T, Xiao X.Clin Chim Acta. 2023 Jan 15;539:250-258.

Liu J#, Xie Z#, Fu J#, Yu M, Wang T, Qi C, Liu P, Hui X, Wang D, Ding L, Zhang Q, Xie T, Xiao X

Liu J#, Wang D#, Xie Z, Ding L, Li S, Ma X, Liu J, Ren J, Xiao C, Yang C, Xiao X. Biomolecules. 2023 Jul 31;13(8):1199

Liu J#, Li T#, Zhang S, Lu E, Qiao W, Chen H, Liu P, Tang X, Cheng T, Chen H.Front Pharmacol. 2023 Oct 9;14:1232539.

马兜铃酸类物质的生物标记物与减毒策略研究进展[J]

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