This laboratory seeks to establish multidimensional, comprehensive key technologies and research systems for early clinical evaluation of innovative drugs and devices, with the focus on major diseases including tumors, rare diseases, cardiovascular and cerebrovascular diseases, neurodegenerative diseases, diabetes, and autoimmune diseases. Leveraging interdisciplinary collaboration and partnerships with enterprises, the laboratory develops new technologies and methods to empower clinical research. It discovers, summarizes, and consolidates design strategies and technical solutions for first-in-human trials of innovative drugs in specialized fields, improving the translational efficiency of clinically valuable innovative drugs and devices from pre-clinical to clinical stages. The laboratory enhances the quality and efficiency of innovative drug and device clinical research in Beijing by providing strong technical support, thereby promoting the sustained development of this field citywide and nationwide.